ADAMTS14

Across TCGA patient cohorts, ADAMTS14 mutation is significantly associated with the total protein of many other genes, with 57 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADAMTS14-associated genes across cancer lineages are MYH11, ATM, and Rictor. Each is linked with ADAMTS14 in more than 4 cancer types. Because this analysis shows association rather than direction, both ADAMTS14-to-partner and partner-to-ADAMTS14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYH11 grouped by ADAMTS14-low versus ADAMTS14-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMTS14→partner) and Y-score (partner→ADAMTS14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	MYH11 →	-1.345	-3.000	.037	.034	2	5
UCEC	ATM →	-0.459	-1.834	<.001	.007	3	4
LUAD	Rictor →	-0.389	-2.906	.027	.001	3	3
STAD	eIF4E →	+0.263	+2.459	<.001	.019	3	3
COAD	FASN →	+0.679	+3.178	<.001	.010	2	4
STAD	ASNS →	+0.414	+3.000	.031	.033	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 57 associations by consensus.

MYH11 by ADAMTS14 expression — STAD

Explore this box plot interactively →