ADAMTS14

Across TCGA cell cohorts, ADAMTS14 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,264 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ADAMTS14-associated GO terms across cancer lineages are Negative regulation of cytokine production, Maintenance of protein localization in organelle, and Response to acid chemical. Each is linked with ADAMTS14 in more than 9 cancer types. Because this analysis shows association rather than direction, both ADAMTS14-to-partner and partner-to-ADAMTS14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cytokine production grouped by ADAMTS14-low versus ADAMTS14-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMTS14→partner) and Y-score (partner→ADAMTS14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Negative regulation of cytokine production →	+0.043	+0.891	<.001	.002	3	9
BREAST	Maintenance of protein localization in organelle →	+0.129	+0.724	<.001	<.001	3	9
BONE	Response to acid chemical →	+0.088	+1.627	<.001	.002	3	9
OVARY	Negative regulation of myoblast fusion →	+0.077	+0.780	.005	.009	2	10
BREAST	Antigen processing and presentation of exogenous peptide antigen via MHC class Ib →	+0.277	+0.685	<.001	<.001	3	9
OESOPHAGUS	Viral process →	+0.074	+0.632	.001	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,264 associations by consensus.

Negative regulation of cytokine production by ADAMTS14 expression — CNS

Explore this box plot interactively →