ADAMTS14

Across TCGA cell cohorts, ADAMTS14 mutation is significantly associated with the RNA expression of many other genes, with 539 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ADAMTS14-associated genes across cancer lineages are ZAN, DGAT2L6, and LILRA1. Each is linked with ADAMTS14 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADAMTS14-to-partner and partner-to-ADAMTS14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZAN grouped by ADAMTS14-low versus ADAMTS14-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAMTS14→partner) and Y-score (partner→ADAMTS14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	ZAN →	+0.006	+5.369	<.001	.004	3	2
OESOPHAGUS	DGAT2L6 →	+0.006	+4.906	<.001	.006	3	1
SOFT_TISSUE	LILRA1 →	+0.113	+4.930	<.001	.008	3	1
SOFT_TISSUE	OR7E24 →	+0.029	+5.369	<.001	.004	3	1
SOFT_TISSUE	TARM1 →	+0.052	+5.369	<.001	.004	3	1
PANCREAS	NAT8B →	+0.145	+4.011	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 539 associations by consensus.

ZAN by ADAMTS14 expression — SOFT_TISSUE

Explore this box plot interactively →