ADAM7

Across TCGA patient cohorts, ADAM7 mutation is significantly associated with the RNA expression of many other genes, with 4,892 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADAM7-associated genes across cancer lineages are VN1R38P, DSCR8, and MTCO1P3. Each is linked with ADAM7 in more than 2 cancer types. Because this analysis shows association rather than direction, both ADAM7-to-partner and partner-to-ADAM7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VN1R38P grouped by ADAM7-low versus ADAM7-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAM7→partner) and Y-score (partner→ADAM7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	VN1R38P →	+0.113	+5.547	<.001	<.001	3	3
CESC	DSCR8 →	+1.029	+3.926	<.001	.004	3	3
CESC	MTCO1P3 →	+0.269	+3.900	.009	.004	3	3
SKCM	ACTBP13 →	+0.012	+0.808	.008	.009	3	3
SKCM	MTND2P8 →	+0.010	+1.302	.004	.002	3	3
SKCM	KRT8P35 →	+0.030	+0.992	.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,892 associations by consensus.

VN1R38P by ADAM7 expression — LIHC

Explore this box plot interactively →