ADAM5

Q-omics provides the consensus-scored ADAM5 profile across patient tissues and cancer cell-line models. ADAM5 expression is associated with patient survival in 14 of 34 cancer types, with the highest sampling consensus in KIRC. Additionally, ADAM5 RNA expression shows 6,138 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight KIRC, and STAD as cancer lineages where ADAM5 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes ADAM5 survival associations across molecular data types. ADAM5 RNA expression shows survival associations in the most cancer types (14), followed by mutation status (1). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

ADAM5 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	14	KIRC (99)	view →
Mutation	Kaplan–Meier	1	UCEC (12)	view →

This table ranks reproducible ADAM5 RNA expression–survival associations across cancer types. High ADAM5 expression shows unfavorable associations in KIRC, ACC, MESO, THYM and UVM, but favorable associations in HNSC. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for ADAM5 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.495	0.689	<.001	99	view →
ACC	OS	Tertile	All	0.415	0.699	<.001	88	view →
MESO	OS	Tertile	All	0.343	0.582	<.001	63	view →
THYM	DFS	Tertile	All	0.688	0.894	.001	39	view →
HNSC	DFS	Tertile	IV	0.716	0.535	.018	36	view →
UVM	OS	Tertile	III,IV	0.136	0.874	<.001	33	view →

Pink = unfavorable, green = favorable. all 14 lineages →

ADAM5-KIRC (OS)

Explore this curve interactively →