ADAM23

Across TCGA patient cohorts, ADAM23 protein abundance is significantly associated with the RNA expression of many other genes, with 8,351 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ADAM23-associated genes across cancer lineages are PRODH, SNU13, and SYNGR1. Each is linked with ADAM23 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADAM23-to-partner and partner-to-ADAM23 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADAM23 versus PRODH in GBM, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAM23→partner) and Y-score (partner→ADAM23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRODH →	+0.908	+0.573	<.001	<.001	3	2
LSCC	SNU13 →	+0.325	+1.013	.001	.002	3	2
LSCC	SYNGR1 →	+0.954	+1.873	<.001	<.001	3	2
LSCC	KIAA0930 →	+0.551	+1.340	<.001	<.001	3	2
GBM	RANGAP1 →	+0.378	+0.698	.001	<.001	3	2
LSCC	DESI1 →	+0.350	+1.270	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,351 associations by consensus.

ADAM23 vs PRODH — GBM

Explore this scatter interactively →