ADAM22

Across TCGA patient cohorts, ADAM22 protein abundance is significantly associated with the RNA expression of many other genes, with 8,903 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ADAM22-associated genes across cancer lineages are LINC01338, NRIP3, and SHANK1. Each is linked with ADAM22 in more than 2 cancer types. Because this analysis shows association rather than direction, both ADAM22-to-partner and partner-to-ADAM22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADAM22 versus LINC01338 in GBM, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAM22→partner) and Y-score (partner→ADAM22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LINC01338 →	+0.575	+0.377	.009	.008	3	3
GBM	NRIP3 →	+0.880	+0.496	<.001	<.001	3	3
OV	SHANK1 →	+0.788	+1.311	.007	<.001	3	2
OV	PPP1R14A →	+2.583	+1.710	<.001	.005	3	2
GBM	PTCRA →	+0.715	+0.596	.001	<.001	3	2
OV	PGP →	+0.821	+1.333	.004	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,903 associations by consensus.

ADAM22 vs LINC01338 — GBM

Explore this scatter interactively →