ADAM21P1

Across TCGA patient cohorts, ADAM21P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,695 significant associations in total. THYM shows the largest number of these associations.

The most reproducible ADAM21P1-associated GO terms across cancer lineages are Negative regulation of telomere capping, Transcription by RNA polymerase III, and Regulation of proteasomal protein catabolic process. Each is linked with ADAM21P1 in more than 20 cancer types. Because this analysis shows association rather than direction, both ADAM21P1-to-partner and partner-to-ADAM21P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of telomere capping grouped by ADAM21P1-low versus ADAM21P1-high in THYM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAM21P1→partner) and Y-score (partner→ADAM21P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	Negative regulation of telomere capping →	+0.052	+0.042	<.001	<.001	3	21
THYM	Transcription by RNA polymerase III →	+0.036	+0.033	<.001	<.001	3	20
STAD	Regulation of proteasomal protein catabolic process →	+0.038	+0.050	<.001	.001	3	19
STAD	Protein localization to chromosome, telomeric region →	+0.035	+0.045	<.001	<.001	3	19
ESCA	Cellular response to light stimulus →	+0.039	+0.023	<.001	.008	2	20
THYM	Obsolete mRNA methylation →	+0.054	+0.041	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,695 associations by consensus.

Negative regulation of telomere capping by ADAM21P1 expression — THYM

Explore this box plot interactively →