ADAM15

Across TCGA patient cohorts, ADAM15 protein abundance is significantly associated with the RNA expression of many other genes, with 7,910 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ADAM15-associated genes across cancer lineages are CUBN, ANK2, and RNF180. Each is linked with ADAM15 in more than 3 cancer types. Because this analysis shows association rather than direction, both ADAM15-to-partner and partner-to-ADAM15 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADAM15 versus CUBN in GBM, with a Pearson correlation of -0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAM15→partner) and Y-score (partner→ADAM15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CUBN →	-0.481	-0.309	<.001	<.001	3	4
OV	ANK2 →	-1.184	-0.680	<.001	<.001	3	4
OV	RNF180 →	-0.599	-0.408	.004	.005	3	4
UCEC	LRFN5 →	-1.172	-0.405	<.001	.002	3	4
HNSC	ASXL1 →	-0.397	-0.227	<.001	<.001	3	4
LSCC	TCF4 →	-0.662	-0.316	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,910 associations by consensus.

ADAM15 vs CUBN — GBM

Explore this scatter interactively →