ADAM15

Across TCGA cell cohorts, ADAM15 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,220 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ADAM15-associated GO terms across cancer lineages are Response to hypobaric hypoxia, Immune response to tumor cell, and Response to tumor cell. Each is linked with ADAM15 in more than 14 cancer types. Because this analysis shows association rather than direction, both ADAM15-to-partner and partner-to-ADAM15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to hypobaric hypoxia grouped by ADAM15-low versus ADAM15-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADAM15→partner) and Y-score (partner→ADAM15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Response to hypobaric hypoxia →	+0.164	+1.220	<.001	<.001	3	15
SOFT_TISSUE	Immune response to tumor cell →	+0.327	+1.292	<.001	<.001	3	14
BONE	Response to tumor cell →	+0.148	+0.898	<.001	.002	3	11
BONE	Actomyosin contractile ring assembly actin filament organization →	+0.211	+1.273	.005	<.001	3	10
BONE	Assembly of actomyosin apparatus involved in cytokinesis →	+0.178	+1.296	.006	.008	2	11
BONE	Actomyosin contractile ring assembly →	+0.178	+1.296	.006	.008	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,220 associations by consensus.

Response to hypobaric hypoxia by ADAM15 expression — BONE

Explore this box plot interactively →