ACY3

Across TCGA patient cohorts, ACY3 protein abundance is significantly associated with the RNA expression of many other genes, with 6,350 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ACY3-associated genes across cancer lineages are STXBP5L, ARHGAP26, and UBA7. Each is linked with ACY3 in more than 2 cancer types. Because this analysis shows association rather than direction, both ACY3-to-partner and partner-to-ACY3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACY3 versus STXBP5L in LSCC, with a Pearson correlation of -0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACY3→partner) and Y-score (partner→ACY3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	STXBP5L →	-0.738	-0.509	.001	.001	3	3
UCEC	ARHGAP26 →	+1.169	+0.891	<.001	<.001	3	3
UCEC	UBA7 →	+0.901	+0.634	.005	.001	3	3
BRCA	HLA-DMA →	+1.034	+0.756	.004	.008	3	3
UCEC	ARHGAP26-IT1 →	+0.929	+0.648	.001	.002	3	3
UCEC	BCO1 →	+1.246	+0.697	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,350 associations by consensus.

ACY3 vs STXBP5L — LSCC

Explore this scatter interactively →