ACY3

Across TCGA cell cohorts, ACY3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,597 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ACY3-associated GO terms across cancer lineages are Basement membrane disassembly, CD8-positive, alpha-beta T cell activation, and Monocarboxylic acid catabolic process. Each is linked with ACY3 in more than 8 cancer types. Because this analysis shows association rather than direction, both ACY3-to-partner and partner-to-ACY3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Basement membrane disassembly grouped by ACY3-low versus ACY3-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACY3→partner) and Y-score (partner→ACY3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Basement membrane disassembly →	+1.681	+1.625	<.001	.002	2	9
LARGE_INTESTINE	CD8-positive, alpha-beta T cell activation →	+0.104	+1.122	.001	.001	2	9
LIVER	Monocarboxylic acid catabolic process →	+0.083	+2.115	<.001	<.001	3	7
URINARY_TRACT	Antigen processing and presentation of peptide antigen →	+0.124	+0.279	.002	.006	2	8
CNS	Negative regulation of glial cell migration →	+0.158	+0.276	.002	.002	3	7
LARGE_INTESTINE	Negative regulation of mast cell degranulation →	+1.214	+1.007	<.001	.004	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,597 associations by consensus.

Basement membrane disassembly by ACY3 expression — LIVER

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