ACY1

Across TCGA patient cohorts, ACY1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,078 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ACY1-associated genes across cancer lineages are RPL29, APEH, and PARP3. Each is linked with ACY1 in more than 3 cancer types. Because this analysis shows association rather than direction, both ACY1-to-partner and partner-to-ACY1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACY1 versus RPL29 in OV, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACY1→partner) and Y-score (partner→ACY1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RPL29 →	+0.720	+0.622	<.001	.001	3	4
BRCA	APEH →	+0.456	+0.574	<.001	<.001	3	4
BRCA	PARP3 →	+0.678	+0.606	<.001	<.001	3	4
OV	QARS1 →	+0.523	+0.561	<.001	.002	3	4
LUAD	CCDC3 →	-0.624	-0.482	<.001	.003	3	3
LUAD	IVL →	-1.165	-0.390	.008	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,078 associations by consensus.

ACY1 vs RPL29 — OV

Explore this scatter interactively →