ACY1

Across TCGA patient cohorts, ACY1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACY1-associated genes across cancer lineages are LARP7P1, RNU6-467P, and MTND6P9. Each is linked with ACY1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACY1-to-partner and partner-to-ACY1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LARP7P1 grouped by ACY1-low versus ACY1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACY1→partner) and Y-score (partner→ACY1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LARP7P1 →	+0.246	+5.186	.001	.007	3	1
UCEC	RNU6-467P →	+0.622	+6.722	<.001	<.001	3	1
UCEC	MTND6P9 →	+0.235	+5.133	<.001	.008	3	1
UCEC	CKS1BP5 →	+0.282	+5.420	<.001	.005	3	1
UCEC	MIR2115 →	+0.610	+5.081	.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

LARP7P1 by ACY1 expression — UCEC

Explore this box plot interactively →