ACY1

Across TCGA cell cohorts, ACY1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,842 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ACY1-associated GO terms across cancer lineages are Amino acid metabolic process, Organic acid catabolic process, and Carboxylic acid catabolic process. Each is linked with ACY1 in more than 11 cancer types. Because this analysis shows association rather than direction, both ACY1-to-partner and partner-to-ACY1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Amino acid metabolic process grouped by ACY1-low versus ACY1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACY1→partner) and Y-score (partner→ACY1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Amino acid metabolic process →	+0.064	+1.202	<.001	<.001	3	12
LARGE_INTESTINE	Organic acid catabolic process →	+0.067	+0.994	<.001	<.001	3	12
LARGE_INTESTINE	Carboxylic acid catabolic process →	+0.067	+0.994	<.001	<.001	3	12
LUNG_SCLC	Fatty acid metabolic process →	+0.060	+1.137	<.001	<.001	3	12
LARGE_INTESTINE	Branched-chain amino acid metabolic process →	+0.091	+0.971	<.001	<.001	3	10
LIVER	tRNA 3'-terminal CCA addition →	+0.150	+1.211	.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,842 associations by consensus.

Amino acid metabolic process by ACY1 expression — LIVER

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