ACTRT1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ACTRT1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,421 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ACTRT1-associated genes across cancer lineages are HILPDA, MMP8, and PLOD3. Each is linked with ACTRT1 in more than 4 cancer types. Because this analysis shows association rather than direction, both ACTRT1-to-partner and partner-to-ACTRT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACTRT1 versus HILPDA in GBM, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTRT1→partner) and Y-score (partner→ACTRT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMHILPDA →+1.607+0.579.002.00234
PDACMMP8 →+0.633+0.712.003.00825
LSCCPLOD3 →+0.764+0.754<.001.00633
CCRCCCOL1A1 →+1.792+0.456<.001.00333
LSCCENO2 →+1.040+0.902.001.00133
CCRCCCOL5A1 →+1.556+0.503<.001.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,421 associations by consensus.

ACTRT1 vs HILPDA — GBM

Per-sample scatter of ACTRT1 vs HILPDA in GBM (Pearson r = 0.34).

Explore this scatter interactively →

Exploration