Across TCGA pan-cancer cohorts, ACTRT1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of ACTRT1’s most consistent transcriptional readouts.
The strongest signal is observed in stomach adenocarcinoma (STAD), where ACTRT1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ACTRT1 is over-expressed in tumor.
STAD and KIRC are the cancer types where ACTRT1 tumor–normal differential expression is most reproducible.