ACTRT1

Across TCGA cell cohorts, ACTRT1 RNA expression is significantly associated with the mutation status of many other genes, with 176 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ACTRT1-associated genes across cancer lineages are DNAH8, ZBTB41, and KMT2A. Each is linked with ACTRT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ACTRT1-to-partner and partner-to-ACTRT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNAH8 grouped by ACTRT1-low versus ACTRT1-high in PANCREAS.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTRT1→partner) and Y-score (partner→ACTRT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	DNAH8 →	+2.817	+0.009	.009	.001	3	3
LUNG_NSCLC_LUSC	ZBTB41 →	+3.514	+0.041	.008	<.001	3	2
PANCREAS	KMT2A →	+3.554	+0.010	.003	.001	3	2
BLOOD_Leukemia	GAL3ST3 →	+3.879	+0.014	<.001	<.001	3	2
BLOOD_Leukemia	KLHL23 →	+5.201	+0.021	.006	<.001	3	2
UPPER_AERODIGESTIVE_TRACT	JAG1 →	+4.870	+0.066	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 176 associations by consensus.

DNAH8 by ACTRT1 expression — PANCREAS

Explore this box plot interactively →