ACTR8

Across TCGA patient cohorts, ACTR8 protein abundance is significantly associated with the RNA expression of many other genes, with 16,344 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ACTR8-associated genes across cancer lineages are NOP56, MRPS26, and FANCD2. Each is linked with ACTR8 in more than 3 cancer types. Because this analysis shows association rather than direction, both ACTR8-to-partner and partner-to-ACTR8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACTR8 versus NOP56 in HNSC, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTR8→partner) and Y-score (partner→ACTR8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	NOP56 →	+0.868	+0.185	.001	<.001	3	4
HNSC	MRPS26 →	+0.816	+0.168	.006	<.001	3	4
GBM	FANCD2 →	+0.956	+0.265	<.001	<.001	3	4
HNSC	H2BC4 →	+0.980	+0.146	.001	.001	3	3
GBM	SNORD69 →	+0.634	+0.228	<.001	<.001	3	3
GBM	SNORD19C →	+0.826	+0.169	<.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,344 associations by consensus.

ACTR8 vs NOP56 — HNSC

Explore this scatter interactively →