ACTR8

Across TCGA cell cohorts, ACTR8 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,680 significant associations in total. CNS shows the largest number of these associations.

The most reproducible ACTR8-associated GO terms across cancer lineages are Microtubule polymerization, Positive regulation of telomere maintenance in response to DNA damage, and Positive regulation of mRNA catabolic process. Each is linked with ACTR8 in more than 15 cancer types. Because this analysis shows association rather than direction, both ACTR8-to-partner and partner-to-ACTR8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule polymerization grouped by ACTR8-low versus ACTR8-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTR8→partner) and Y-score (partner→ACTR8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Microtubule polymerization →	+0.111	+0.790	.001	.001	3	16
KIDNEY	Positive regulation of telomere maintenance in response to DNA damage →	+0.088	+0.822	.007	.004	3	16
STOMACH	Positive regulation of mRNA catabolic process →	+0.057	+0.503	.005	.005	3	16
STOMACH	Microtubule nucleation →	+0.119	+0.686	<.001	.003	3	16
URINARY_TRACT	Positive regulation of pinocytosis →	+0.151	+1.105	<.001	<.001	3	15
KIDNEY	Regulation of mRNA catabolic process →	+0.057	+0.751	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,680 associations by consensus.

Microtubule polymerization by ACTR8 expression — STOMACH

Explore this box plot interactively →