ACSL4

Across TCGA patient cohorts, ACSL4 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,830 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ACSL4-associated proteins across cancer lineages are PLOD2, DOCK11, and SERPINB8. Each is linked with ACSL4 in more than 5 cancer types. Because this analysis shows association rather than direction, both ACSL4-to-partner and partner-to-ACSL4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACSL4 versus PLOD2 in CCRCC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ACSL4→partner) and Y-score (partner→ACSL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	PLOD2 →	+0.740	+0.454	.002	.002	3	6
GBM	DOCK11 →	+0.366	+0.583	<.001	<.001	3	6
BRCA	SERPINB8 →	+0.538	+0.643	<.001	<.001	3	5
GBM	SKAP2 →	+0.629	+0.455	<.001	<.001	3	5
GBM	AMPD3 →	+0.599	+0.573	<.001	<.001	3	5
GBM	ITGAM →	+0.799	+0.654	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,830 associations by consensus.

ACSL4 vs PLOD2 — CCRCC

Explore this scatter interactively →