ACACB

Across TCGA cell cohorts, ACACB mutation is significantly associated with the RNA expression of many other genes, with 2,052 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ACACB-associated genes across cancer lineages are TRNAU1AP, CCDC134, and SUFU. Each is linked with ACACB in more than 2 cancer types. Because this analysis shows association rather than direction, both ACACB-to-partner and partner-to-ACACB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRNAU1AP grouped by ACACB-low versus ACACB-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACACB→partner) and Y-score (partner→ACACB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	TRNAU1AP →	+0.577	+3.307	.001	.005	3	3
LARGE_INTESTINE	CCDC134 →	+0.736	+2.222	<.001	<.001	3	3
LARGE_INTESTINE	SUFU →	+0.413	+1.956	.004	.005	3	3
LARGE_INTESTINE	RELCH →	+0.774	+1.628	<.001	<.001	3	3
LARGE_INTESTINE	SAP30 →	+0.527	+1.961	.009	.004	3	3
LARGE_INTESTINE	HIF1AN →	+0.522	+2.546	.002	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,052 associations by consensus.

TRNAU1AP by ACACB expression — CNS

Explore this box plot interactively →