ABI3BP

Across TCGA patient cohorts, ABI3BP mutation is significantly associated with the RNA expression of many other genes, with 4,016 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABI3BP-associated genes across cancer lineages are ATAD3A, PICK1, and SCO1. Each is linked with ABI3BP in more than 3 cancer types. Because this analysis shows association rather than direction, both ABI3BP-to-partner and partner-to-ABI3BP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATAD3A grouped by ABI3BP-low versus ABI3BP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABI3BP→partner) and Y-score (partner→ABI3BP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATAD3A →	+0.446	+1.554	<.001	<.001	3	4
UCEC	PICK1 →	+0.228	+1.788	.003	.001	3	4
UCEC	SCO1 →	+0.446	+1.954	<.001	<.001	3	4
UCEC	LETM1 →	+0.389	+1.479	<.001	<.001	3	4
UCEC	EWSR1 →	+0.243	+1.949	.001	<.001	3	3
UCEC	PYCR1 →	+0.433	+1.303	.004	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,016 associations by consensus.

ATAD3A by ABI3BP expression — UCEC

Explore this box plot interactively →