ABI3BP

Across TCGA patient cohorts, ABI3BP mutation is significantly associated with the total protein of many other genes, with 67 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABI3BP-associated genes across cancer lineages are PDCD4, Rad50, and ASNS. Each is linked with ABI3BP in more than 2 cancer types. Because this analysis shows association rather than direction, both ABI3BP-to-partner and partner-to-ABI3BP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PDCD4 grouped by ABI3BP-low versus ABI3BP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABI3BP→partner) and Y-score (partner→ABI3BP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDCD4 →	-0.460	-1.440	<.001	<.001	3	3
UCEC	Rad50 →	-0.202	-1.169	<.001	.004	3	3
COAD	ASNS →	+0.540	+3.000	.001	.034	3	3
UCEC	ATM →	-0.378	-1.638	<.001	.004	3	3
UCEC	Caspase-7-cleavedD198 →	+0.449	+1.315	.002	.005	3	3
SKCM	GSK-3a-b_pS21_S9 →	-0.508	-2.321	.015	.035	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 67 associations by consensus.

PDCD4 by ABI3BP expression — UCEC

Explore this box plot interactively →