ABI3BP

Across TCGA cell cohorts, ABI3BP mutation is significantly associated with the RNA expression of many other genes, with 610 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ABI3BP-associated genes across cancer lineages are ABCE1, NOC3L, and ZNF487. Each is linked with ABI3BP in more than 1 cancer types. Because this analysis shows association rather than direction, both ABI3BP-to-partner and partner-to-ABI3BP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ABCE1 grouped by ABI3BP-low versus ABI3BP-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABI3BP→partner) and Y-score (partner→ABI3BP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ABCE1 →	+0.613	+3.169	<.001	.009	3	2
LARGE_INTESTINE	NOC3L →	+0.818	+3.321	<.001	.003	3	2
LARGE_INTESTINE	ZNF487 →	+0.635	+2.502	<.001	.005	3	2
SKIN	GPR15 →	+0.217	+3.333	.005	.009	3	1
SKIN	KRTAP6-1 →	+0.042	+3.700	<.001	.009	3	1
SKIN	CRYAA2 →	+0.031	+3.518	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 610 associations by consensus.

ABCE1 by ABI3BP expression — LARGE_INTESTINE

Explore this box plot interactively →