ABHD17AP6

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ABHD17AP6 mutation is significantly associated with the total protein of many other genes, with 30 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABHD17AP6-associated genes across cancer lineages are 14-3-3_beta, A-Raf_pS299, and JNK_pT183_Y185. Each is linked with ABHD17AP6 in more than 1 cancer types. Because this analysis shows association rather than direction, both ABHD17AP6-to-partner and partner-to-ABHD17AP6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD17AP6→partner) and Y-score (partner→ABHD17AP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCEC14-3-3_beta →-0.088-2.973.045.03531
UCECA-Raf_pS299 →-0.158-3.906.002<.00131
UCECJNK_pT183_Y185 →-0.170-2.102.020.01931
UCECJNK2 →+0.265+3.179.002.01022
UCECKu80 →+0.361+3.335<.001.00531
UCECMEK1 →+0.357+2.115.025.01931
Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

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