ABHD14B

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ABHD14B mutation is significantly associated with the RNA expression of many other genes, with 320 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABHD14B-associated genes across cancer lineages are RNA5SP241, SNORD11B, and RPS29P32. Each is linked with ABHD14B in more than 1 cancer types. Because this analysis shows association rather than direction, both ABHD14B-to-partner and partner-to-ABHD14B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP241 grouped by ABHD14B-low versus ABHD14B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD14B→partner) and Y-score (partner→ABHD14B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNA5SP241 →+0.759+3.242<.001.00132
UCECSNORD11B →+0.653+2.546<.001.00231
UCECRPS29P32 →+0.453+2.599<.001.00931
UCECH2AC16 →+0.855+3.470<.001.00331
UCECTBRG1 →+0.398+3.513.006.00231
UCECSEC13 →+0.525+3.210.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 320 associations by consensus.

RNA5SP241 by ABHD14B expression — UCEC

Box plot of RNA5SP241 in ABHD14B-low vs ABHD14B-high samples in UCEC.

Explore this box plot interactively →

Exploration