ABHD14A

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ABHD14A mutation is significantly associated with the RNA expression of many other genes, with 66 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABHD14A-associated genes across cancer lineages are SNORD3A, MIR5188, and MIR4287. Each is linked with ABHD14A in more than 1 cancer types. Because this analysis shows association rather than direction, both ABHD14A-to-partner and partner-to-ABHD14A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD3A grouped by ABHD14A-low versus ABHD14A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD14A→partner) and Y-score (partner→ABHD14A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECSNORD3A →+0.411+3.428<.001.00131
UCECMIR5188 →+0.728+2.650<.001.00731
UCECMIR4287 →+0.300+4.437<.001.00531
UCECCCDC58P3 →+0.319+3.372.007.00831
UCECEML2-AS1 →+0.091+2.592<.001.00931
UCECVN1R91P →+0.317+3.621<.001.00331
Each partner links to its Q-omics profile. Showing the 6 strongest of 66 associations by consensus.

SNORD3A by ABHD14A expression — UCEC

Box plot of SNORD3A in ABHD14A-low vs ABHD14A-high samples in UCEC.

Explore this box plot interactively →

Exploration