ABHD14A

Across TCGA pan-cancer cohorts, ABHD14A RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of ABHD14A’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where ABHD14A RNA is repressed in tumor relative to normal tissue. In most cancer types ABHD14A is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

KIRC, KICH, and KIRP are the cancer types where ABHD14A tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ABHD14A RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	−0.966	<.001	12	view →
KICH	Female	II,III,IV	−2.051	<.001	11	view →
KIRP	All	III,IV	−0.880	<.001	9	view →
LIHC	Female	II,III,IV	+0.876	<.001	9	view →
LUSC	Male	III,IV	−1.487	<.001	8	view →
BRCA	Female	II,III,IV	−0.436	<.001	6	view →
COAD	Female	All	+0.688	<.001	5	view →
LUAD	All	All	−0.325	.004	4	view →
THCA	Male	III,IV	−0.568	.030	2	view →
CHOL	Male	All	+0.501	.040	2	view →
STAD	Female	III,IV	−0.544	.023	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

ABHD14A–KIRC

Open the KIRC breakdown →