ABHD14A

Across TCGA pan-cancer cohorts, ABHD14A RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated ABHD14A data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher ABHD14A RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ABHD14A expression acts as an unfavorable survival marker, although some lineages such as KIRP and BRCA show a favorable association.

KIRP, BRCA, and LGG are the cancer types where ABHD14A RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Tertile	All	0.964	0.833	<.001	88	view →
BRCA	OS	Median	All	0.952	0.897	<.001	59	view →
LGG	DFS	Median	All	0.839	0.642	<.001	52	view →
KIRC	DFS	Median	II,III,IV	0.525	0.761	.001	50	view →
UCS	OS	Median	III,IV	0.273	0.612	.004	32	view →
PAAD	DFS	Tertile	All	0.413	0.167	.005	29	view →
ACC	DFS	Quartile	All	0.120	0.755	.001	29	view →
LUSC	OS	Tertile	II,III,IV	0.529	0.733	.009	17	view →
LIHC	DFS	Quartile	III,IV	0.240	0.612	.015	17	view →
DLBC	DFS	Median	All	0.858	0.358	.010	12	view →
KICH	OS	Median	All	0.784	0.969	.023	7	view →
LUAD	OS	Tertile	All	0.862	0.769	.005	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

ABHD14A–KIRP (DFS)

Open the KIRP breakdown →