ABHD14A-ACY1

Across TCGA patient cohorts, ABHD14A-ACY1 mutation is significantly associated with the total protein of many other genes, with 25 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABHD14A-ACY1-associated genes across cancer lineages are EGFR_pY1173, eIF4G, and FoxM1. Each is linked with ABHD14A-ACY1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ABHD14A-ACY1-to-partner and partner-to-ABHD14A-ACY1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EGFR_pY1173 grouped by ABHD14A-ACY1-low versus ABHD14A-ACY1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD14A-ACY1→partner) and Y-score (partner→ABHD14A-ACY1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1173 →	+0.063	+1.611	.045	.022	3	1
UCEC	eIF4G →	+0.248	+2.999	.041	.035	3	1
UCEC	FoxM1 →	+0.263	+2.000	.009	.010	3	1
UCEC	FOXO3a_pS318_S321 →	-0.114	-1.690	.019	.042	3	1
UCEC	INPP4B →	-0.269	-2.321	.034	.033	3	1
UCEC	JNK_pT183_Y185 →	-0.161	-1.571	.015	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

EGFR_pY1173 by ABHD14A-ACY1 expression — UCEC

Explore this box plot interactively →