ABHD14A-ACY1

Across TCGA pan-cancer cohorts, ABHD14A-ACY1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated ABHD14A-ACY1 data layer compared with 6 for mutation status.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher ABHD14A-ACY1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ABHD14A-ACY1 expression acts as an unfavorable survival marker, although some lineages such as KIRP and BLCA show a favorable association.

ACC, KIRC, and KIRP are the cancer types where ABHD14A-ACY1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.264	0.596	<.001	82	view →
KIRC	DFS	Tertile	All	0.496	0.692	.003	63	view →
KIRP	OS	Tertile	II,III,IV	0.823	0.490	.002	53	view →
UVM	DFS	Quartile	III,IV	0.104	1.000	.006	34	view →
BLCA	OS	Tertile	All	0.699	0.542	.003	29	view →
UCEC	DFS	Median	II,III,IV	0.654	0.804	.005	20	view →
SARC	OS	Tertile	All	0.367	0.661	<.001	19	view →
MESO	OS	Median	IV	0.378	0.756	.017	15	view →
THYM	DFS	Tertile	All	0.926	0.795	.025	14	view →
SKCM	DFS	Quartile	II,III,IV	0.499	0.731	.010	11	view →
PRAD	DFS	Quartile	All	0.789	0.917	.001	10	view →
LGG	OS	Tertile	All	0.950	0.802	<.001	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

ABHD14A-ACY1–ACC (DFS)

Open the ACC breakdown →