ABHD14A-ACY1

Across TCGA pan-cancer cohorts, ABHD14A-ACY1 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of ABHD14A-ACY1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where ABHD14A-ACY1 RNA is repressed in tumor relative to normal tissue. In most cancer types ABHD14A-ACY1 is over-expressed in tumor, although a few such as KIRP and KIRC show the opposite, repressed pattern.

KIRP, COAD, and KIRC are the cancer types where ABHD14A-ACY1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ABHD14A-ACY1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	III,IV	−0.774	<.001	11	view →
COAD	Female	All	+0.502	<.001	11	view →
KIRC	Male	All	−0.389	<.001	8	view →
KICH	Female	All	−0.543	<.001	7	view →
LUAD	All	All	+0.144	<.001	4	view →
BLCA	All	III,IV	+0.184	.031	3	view →
LIHC	All	All	+0.159	<.001	3	view →
LUSC	Male	All	+0.086	.019	3	view →
STAD	Female	All	+0.240	.015	2	view →
ESCA	All	All	+0.213	.028	2	view →
PRAD	All	All	+0.131	.001	2	view →
BRCA	Female	All	−0.059	.020	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

ABHD14A-ACY1–KIRP

Open the KIRP breakdown →