ABHD14A-ACY1

Across TCGA cell cohorts, ABHD14A-ACY1 mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ABHD14A-ACY1-associated genes across cancer lineages are OPRPN, CYLC1, and CFHR2. Each is linked with ABHD14A-ACY1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ABHD14A-ACY1-to-partner and partner-to-ABHD14A-ACY1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OPRPN grouped by ABHD14A-ACY1-low versus ABHD14A-ACY1-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD14A-ACY1→partner) and Y-score (partner→ABHD14A-ACY1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	OPRPN →	+0.018	+5.000	.001	.006	3	1
PANCREAS	CYLC1 →	+0.006	+5.614	<.001	.002	3	1
PANCREAS	CFHR2 →	+0.013	+5.614	<.001	.002	3	1
BLOOD_Leukemia	NKX2-6 →	+0.591	+5.201	<.001	.006	3	1
BLOOD_Leukemia	TLE7 →	+0.042	+5.969	<.001	.001	3	1
LARGE_INTESTINE	SLC5A5 →	+0.327	+3.716	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

OPRPN by ABHD14A-ACY1 expression — PANCREAS

Explore this box plot interactively →