ABCG8

Across TCGA cell cohorts, ABCG8 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,595 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ABCG8-associated GO terms across cancer lineages are Fertilization, Stress granule assembly, and Oocyte growth. Each is linked with ABCG8 in more than 6 cancer types. Because this analysis shows association rather than direction, both ABCG8-to-partner and partner-to-ABCG8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Fertilization grouped by ABCG8-low versus ABCG8-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCG8→partner) and Y-score (partner→ABCG8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Fertilization →	-0.093	-0.056	<.001	.006	3	6
BONE	Stress granule assembly →	+0.079	+0.017	.001	.005	2	7
BLOOD_Lymphoma	Oocyte growth →	+0.146	+0.013	.001	<.001	2	7
BLOOD_Leukemia	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.064	+0.008	.002	.002	2	7
SKIN	Regulation of myoblast fusion →	+0.065	+0.014	.002	.004	3	5
BONE	Regulation of RNA splicing →	+0.063	+0.020	.002	.008	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,595 associations by consensus.

Fertilization by ABCG8 expression — OVARY

Explore this box plot interactively →