ABCC2

Across TCGA patient cohorts, ABCC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,150 significant associations in total. THCA shows the largest number of these associations.

The most reproducible ABCC2-associated GO terms across cancer lineages are Mitotic G2/M transition checkpoint, Peptidyl-serine autophosphorylation, and Histone mRNA catabolic process. Each is linked with ABCC2 in more than 23 cancer types. Because this analysis shows association rather than direction, both ABCC2-to-partner and partner-to-ABCC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic G2/M transition checkpoint grouped by ABCC2-low versus ABCC2-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCC2→partner) and Y-score (partner→ABCC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Mitotic G2/M transition checkpoint →	+0.088	+0.404	<.001	<.001	3	24
SCLC	Peptidyl-serine autophosphorylation →	+0.110	+0.467	<.001	<.001	3	23
DLBC	Histone mRNA catabolic process →	+0.124	+0.484	<.001	<.001	3	23
DLBC	Telomere organization →	+0.072	+0.411	<.001	<.001	3	22
DLBC	Regulation of telomere maintenance →	+0.093	+0.488	<.001	<.001	3	22
THYM	Retrograde transport, vesicle recycling within Golgi →	+0.066	+0.422	<.001	<.001	2	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,150 associations by consensus.

Mitotic G2/M transition checkpoint by ABCC2 expression — DLBC

Explore this box plot interactively →