ABCC2

Across TCGA cell cohorts, ABCC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,063 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ABCC2-associated GO terms across cancer lineages are Leukotriene transport, Cellular response to jasmonic acid stimulus, and Response to jasmonic acid. Each is linked with ABCC2 in more than 8 cancer types. Because this analysis shows association rather than direction, both ABCC2-to-partner and partner-to-ABCC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Leukotriene transport grouped by ABCC2-low versus ABCC2-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCC2→partner) and Y-score (partner→ABCC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Leukotriene transport →	+0.591	+2.472	<.001	<.001	3	9
LUNG_NSCLC_LUAD	Cellular response to jasmonic acid stimulus →	+1.279	+3.656	<.001	<.001	3	8
LUNG_NSCLC_LUAD	Response to jasmonic acid →	+1.279	+3.656	<.001	<.001	3	8
OESOPHAGUS	Menaquinone catabolic process →	+1.255	+1.835	<.001	<.001	2	9
LIVER	Alcohol catabolic process →	+0.165	+3.930	.006	.002	3	8
LUNG_NSCLC_LUAD	Bile acid and bile salt transport →	+0.064	+2.676	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,063 associations by consensus.

Leukotriene transport by ABCC2 expression — SKIN

Explore this box plot interactively →