ABCC12

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ABCC12 RNA expression is significantly associated with the go_rna of many other GO terms, with 915 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ABCC12-associated GO terms across cancer lineages are Response to carbon monoxide, Protein-RNA complex disassembly, and Negative regulation of leukocyte cell-cell adhesion. Each is linked with ABCC12 in more than 3 cancer types. Because this analysis shows association rather than direction, both ABCC12-to-partner and partner-to-ABCC12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to carbon monoxide grouped by ABCC12-low versus ABCC12-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCC12→partner) and Y-score (partner→ABCC12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BREASTResponse to carbon monoxide →-0.137-0.910.004.00234
LUNG_NSCLC_LUADProtein-RNA complex disassembly →+0.076+0.047.002.00933
BLOOD_LymphomaNegative regulation of leukocyte cell-cell adhesion →+0.047+0.018.008.00933
BLOOD_LymphomaResponse to type I interferon →+0.097+0.020<.001.00533
BLOOD_LymphomaRegulation of viral process →+0.080+0.031<.001.00233
BLOOD_LymphomaCellular response to type I interferon →+0.084+0.036.001.00633
Each partner links to its Q-omics profile. Showing the 6 strongest of 915 associations by consensus.

Response to carbon monoxide by ABCC12 expression — BREAST

Box plot of Response to carbon monoxide in ABCC12-low vs ABCC12-high samples in BREAST.

Explore this box plot interactively →

Exploration