ABCC12

Across TCGA pan-cancer cohorts, ABCC12 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated ABCC12 data layer compared with 12 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ABCC12 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ABCC12 expression acts as an unfavorable survival marker, although some lineages such as LUAD and UCS show a favorable association.

KIRC, BLCA, and UVM are the cancer types where ABCC12 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.512	0.681	<.001	121	view →
BLCA	DFS	Tertile	All	0.486	0.648	<.001	108	view →
UVM	OS	Tertile	All	0.470	0.761	.001	75	view →
LUAD	OS	Median	All	0.435	0.292	<.001	55	view →
UCS	DFS	Tertile	II,III,IV	0.629	0.204	.002	48	view →
CESC	OS	Tertile	III,IV	0.553	0.828	.005	30	view →
MESO	OS	Tertile	All	0.200	0.705	.004	27	view →
OV	DFS	Quartile	All	0.623	0.489	.003	24	view →
CHOL	OS	Tertile	All	0.270	0.689	.006	24	view →
DLBC	OS	Quartile	II,III,IV	0.596	1.000	.038	20	view →
COAD	OS	Tertile	II,III,IV	0.353	0.621	.005	18	view →
THYM	OS	Quartile	All	0.728	1.000	.011	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

ABCC12–KIRC (DFS)

Open the KIRC breakdown →