ABCC10

Across TCGA pan-cancer cohorts, ABCC10 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated ABCC10 data layer compared with 21 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ABCC10 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated ABCC10 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

HNSC, UCEC, and KICH are the cancer types where ABCC10 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	II,III,IV	0.190	0.613	.018	18	view →
UCEC	DFS	Median	All	0.963	0.825	.009	16	view →
KICH	DFS	Median	All	0.102	0.848	.004	13	view →
BRCA	OS	Median	All	0.348	0.925	<.001	12	view →
SCLC	DFS	Median	All	0.192	0.793	.017	6	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

ABCC10–HNSC (DFS)

Open the HNSC breakdown →