ABCC10

Across TCGA pan-cancer cohorts, ABCC10 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ABCC10 data layer compared with 21 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher ABCC10 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated ABCC10 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LSCC show a favorable association.

PDAC, HNSC, and CCRCC are the cancer types where ABCC10 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Quartile	All	0.287	0.598	.010	10	view →
HNSC	DFS	Tertile	IV	0.551	0.835	.017	10	view →
CCRCC	DFS	Median	III,IV	0.089	0.710	.038	6	view →
LUAD	OS	Tertile	III,IV	0.879	0.478	.016	6	view →
LSCC	OS	Median	III,IV	0.849	0.474	.027	5	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ABCC10–PDAC (DFS)

Open the PDAC breakdown →