ABCB9

Across TCGA patient cohorts, ABCB9 mutation is significantly associated with the RNA expression of many other genes, with 5,673 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABCB9-associated genes across cancer lineages are MIR3661, RNU6-376P, and PLD6. Each is linked with ABCB9 in more than 1 cancer types. Because this analysis shows association rather than direction, both ABCB9-to-partner and partner-to-ABCB9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR3661 grouped by ABCB9-low versus ABCB9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCB9→partner) and Y-score (partner→ABCB9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR3661 →	+0.500	+1.479	.001	.006	3	2
LUSC	RNU6-376P →	+0.284	+4.548	<.001	.009	3	2
UCEC	PLD6 →	+0.532	+2.032	<.001	<.001	3	2
UCEC	OAZ2 →	+0.327	+2.295	.001	.005	3	2
UCEC	POLR2A →	+0.815	+3.169	<.001	<.001	3	2
UCEC	TIGIT →	+0.649	+2.678	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,673 associations by consensus.

MIR3661 by ABCB9 expression — UCEC

Explore this box plot interactively →