ABCB1

Across TCGA patient cohorts, ABCB1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,154 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ABCB1-associated genes across cancer lineages are APOD, HNRNPA1P9, and PGK1. Each is linked with ABCB1 in more than 4 cancer types. Because this analysis shows association rather than direction, both ABCB1-to-partner and partner-to-ABCB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ABCB1 versus APOD in BRCA, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCB1→partner) and Y-score (partner→ABCB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	APOD →	+3.416	+0.742	<.001	<.001	3	5
CCRCC	HNRNPA1P9 →	+0.659	+0.439	<.001	<.001	3	5
GBM	PGK1 →	-0.699	-0.589	<.001	<.001	3	4
LSCC	USP37 →	-0.405	-0.303	.003	.002	3	4
UCEC	KIF23 →	-0.909	-0.591	<.001	<.001	3	4
UCEC	CEP55 →	-0.809	-0.381	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,154 associations by consensus.

ABCB1 vs APOD — BRCA

Explore this scatter interactively →