ABCB1

Across TCGA patient cohorts, ABCB1 protein abundance is significantly associated with the protein abundance of many other proteins, with 20,669 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ABCB1-associated proteins across cancer lineages are NAA50, SPTBN1_S2128, and CA4. Each is linked with ABCB1 in more than 5 cancer types. Because this analysis shows association rather than direction, both ABCB1-to-partner and partner-to-ABCB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ABCB1 versus NAA50 in BRCA, with a Pearson correlation of -0.59.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCB1→partner) and Y-score (partner→ABCB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NAA50 →	-0.498	-0.702	<.001	.001	3	6
GBM	SPTBN1_S2128 →	+0.480	+0.411	<.001	.001	3	5
PDAC	CA4 →	+0.870	+0.623	.001	<.001	3	5
OV	GMPS →	-0.860	-0.867	.004	.001	3	5
GBM	RCOR1 →	-0.344	-0.359	<.001	<.001	3	4
LSCC	RCOR1_S127 →	-0.524	-0.313	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,669 associations by consensus.

ABCB1 vs NAA50 — BRCA

Explore this scatter interactively →