ABCB1

Across TCGA cell cohorts, ABCB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,329 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ABCB1-associated GO terms across cancer lineages are Isoprenoid transport, Terpenoid transport, and Cytoplasmic translation. Each is linked with ABCB1 in more than 7 cancer types. Because this analysis shows association rather than direction, both ABCB1-to-partner and partner-to-ABCB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Isoprenoid transport grouped by ABCB1-low versus ABCB1-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCB1→partner) and Y-score (partner→ABCB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Isoprenoid transport →	+1.513	+2.996	<.001	<.001	3	8
LARGE_INTESTINE	Terpenoid transport →	+1.513	+2.996	<.001	<.001	3	8
SOFT_TISSUE	Cytoplasmic translation →	+0.050	+0.562	.001	.004	3	7
BONE	Neuroligin clustering involved in postsynaptic membrane assembly →	+1.432	+1.255	<.001	<.001	3	6
SOFT_TISSUE	Adenylate cyclase-modulating G protein-coupled receptor signaling pathway →	-0.049	-0.505	<.001	.002	3	6
LARGE_INTESTINE	Sulfur compound metabolic process →	+0.041	+1.768	.001	.009	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,329 associations by consensus.

Isoprenoid transport by ABCB1 expression — LARGE_INTESTINE

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