ABCA17P

Across TCGA patient cohorts, ABCA17P mutation is significantly associated with the total protein of many other genes, with 42 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABCA17P-associated genes across cancer lineages are eEF2, EGFR_pY1068, and A-Raf_pS299. Each is linked with ABCA17P in more than 1 cancer types. Because this analysis shows association rather than direction, both ABCA17P-to-partner and partner-to-ABCA17P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by ABCA17P-low versus ABCA17P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCA17P→partner) and Y-score (partner→ABCA17P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.459	+2.222	.002	.011	3	1
UCEC	EGFR_pY1068 →	-0.297	-2.222	.005	.011	3	1
UCEC	A-Raf_pS299 →	-0.153	-2.321	.002	.034	3	1
UCEC	FASN →	+0.398	+3.169	.017	.019	3	1
UCEC	FoxM1 →	+0.235	+2.222	.032	.011	3	1
UCEC	FOXO3a_pS318_S321 →	-0.135	-2.906	.010	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

eEF2 by ABCA17P expression — UCEC

Explore this box plot interactively →