ABCA17P

Across TCGA pan-cancer cohorts, ABCA17P RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated ABCA17P data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher ABCA17P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ABCA17P expression acts as an unfavorable survival marker, although some lineages such as UVM and LUAD show a favorable association.

KIRP, UVM, and LUAD are the cancer types where ABCA17P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Median	All	0.788	0.935	<.001	137	view →
UVM	OS	Median	All	0.828	0.421	<.001	99	view →
LUAD	OS	Quartile	II,III,IV	0.815	0.596	.001	87	view →
UCEC	DFS	Tertile	All	0.858	0.933	.001	48	view →
KICH	DFS	Median	All	0.670	1.000	.004	47	view →
CESC	OS	Tertile	III,IV	0.731	0.297	.010	34	view →
LGG	OS	Tertile	All	0.864	0.716	<.001	31	view →
KIRC	DFS	Tertile	All	0.559	0.723	.001	30	view →
MESO	DFS	Median	IV	0.153	0.474	.001	28	view →
COAD	DFS	Tertile	All	0.612	0.772	.001	21	view →
PRAD	DFS	Median	All	0.700	0.884	<.001	18	view →
SKCM	DFS	Median	III,IV	0.381	0.153	.001	17	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

ABCA17P–KIRP (DFS)

Open the KIRP breakdown →