ABCA17P

Across TCGA pan-cancer cohorts, ABCA17P RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of ABCA17P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where ABCA17P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ABCA17P is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

KIRC, KIRP, and BRCA are the cancer types where ABCA17P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ABCA17P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	+0.728	<.001	12	view →
KIRP	All	II,III,IV	+0.863	.001	8	view →
BRCA	All	All	+0.199	<.001	8	view →
THCA	Male	All	−0.282	<.001	7	view →
LIHC	Male	All	+0.083	<.001	6	view →
HNSC	All	All	+0.222	.017	4	view →
CHOL	All	All	+0.243	.006	3	view →
KICH	Female	All	−0.242	<.001	3	view →
UCEC	All	II,III,IV	−0.385	.009	2	view →
COAD	All	All	+0.252	.019	2	view →
LUAD	All	All	+0.225	.008	2	view →
LUSC	All	All	+0.224	.005	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

ABCA17P–KIRC

Open the KIRC breakdown →