ABCA10

Across TCGA patient cohorts, ABCA10 mutation is significantly associated with the RNA expression of many other genes, with 4,790 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABCA10-associated genes across cancer lineages are OIP5, TIMM44, and TRAIP. Each is linked with ABCA10 in more than 5 cancer types. Because this analysis shows association rather than direction, both ABCA10-to-partner and partner-to-ABCA10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OIP5 grouped by ABCA10-low versus ABCA10-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABCA10→partner) and Y-score (partner→ABCA10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	OIP5 →	+0.859	+3.608	<.001	.001	3	6
UCEC	TIMM44 →	+0.509	+2.161	<.001	<.001	3	6
UCEC	TRAIP →	+0.535	+1.949	<.001	<.001	3	6
LUAD	SKA1 →	+0.809	+3.709	<.001	<.001	2	6
UCEC	MELK →	+0.605	+2.081	<.001	<.001	3	5
UCEC	SKA3 →	+0.518	+1.562	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,790 associations by consensus.

OIP5 by ABCA10 expression — LUAD

Explore this box plot interactively →