AASS

Across TCGA patient cohorts, AASS protein abundance is significantly associated with the RNA expression of many other genes, with 9,945 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible AASS-associated genes across cancer lineages are KLF15, FBLN5, and AQP4-AS1. Each is linked with AASS in more than 5 cancer types. Because this analysis shows association rather than direction, both AASS-to-partner and partner-to-AASS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AASS versus KLF15 in OV, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AASS→partner) and Y-score (partner→AASS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	KLF15 →	+1.060	+0.578	<.001	<.001	3	6
UCEC	FBLN5 →	+1.134	+0.561	<.001	<.001	3	5
GBM	AQP4-AS1 →	+0.872	+0.362	<.001	<.001	3	5
UCEC	SOCS2 →	+1.007	+0.580	.001	<.001	3	5
CCRCC	AOX1 →	+1.593	+0.351	.001	.003	3	5
HNSC	ARHGAP24 →	+0.909	+0.563	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,945 associations by consensus.

AASS vs KLF15 — OV

Explore this scatter interactively →